UNC13D Protein (Myc-DYKDDDDK Tag)
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- Target See all UNC13D Proteins
- UNC13D (Unc-13 Homolog D (UNC13D))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UNC13D protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human UNC13D protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UNC13D Protein
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Unc-13 Homolog D (UNC13D) (AA 2-100) protein (GST tag)
UNC13D Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Unc-13 Homolog D (UNC13D) (AA 1-1090) protein (Strep Tag)Crystallography grade UNC13D Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- UNC13D (Unc-13 Homolog D (UNC13D))
- Alternative Name
- Unc13d (UNC13D Products)
- Synonyms
- FHL3 Protein, HLH3 Protein, HPLH3 Protein, Munc13-4 Protein, UNC13D Protein, 2610108D09Rik Protein, Jinx Protein, mFLJ00067 Protein, Unc13h4 Protein, BIGH3 Protein, CDB1 Protein, CDG2 Protein, CDGG1 Protein, CSD Protein, CSD1 Protein, CSD2 Protein, CSD3 Protein, EBMD Protein, LCD1 Protein, unc-13 homolog D Protein, unc-13 homolog D (C. elegans) Protein, transforming growth factor beta induced Protein, UNC13D Protein, Unc13d Protein, TGFBI Protein, unc13d Protein, un13d Protein
- Background
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
- Molecular Weight
- 123.1 kDa
- NCBI Accession
- NP_954712
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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