UNC45B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all UNC45B Proteins
- UNC45B (Unc-45 Homolog B (UNC45B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UNC45B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human UNC45B (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UNC45B Protein
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Unc-45 Homolog B (UNC45B) (AA 1-850) protein (GST tag)
UNC45B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Unc-45 Homolog B (UNC45B) (AA 1-931) protein (Strep Tag)Crystallography grade UNC45B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- UNC45B (Unc-45 Homolog B (UNC45B))
- Alternative Name
- Unc45b (UNC45B Products)
- Synonyms
- MGC80931 Protein, cmya4 Protein, AA445617 Protein, Cmya4 Protein, D230041A13Rik Protein, Unc45 Protein, CMYA4 Protein, SMUNC45 Protein, UNC45 Protein, Unc-45B Protein, cb393 Protein, unc45r Protein, wu:fa05a03 Protein, wu:fa10f03 Protein, wu:fb37f02 Protein, wu:fb96f06 Protein, wu:fc10f04 Protein, unc-45 myosin chaperone B S homeolog Protein, unc-45 myosin chaperone B Protein, unc45b.S Protein, unc45b Protein, UNC45B Protein, Unc45b Protein
- Background
- This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 103.6 kDa
- NCBI Accession
- NP_775259
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