RENT1/UPF1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735034

Product Details

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RENT1/UPF1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UPF1 / RENT1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Alternative Name: Upf1,rent1 (UPF1 Products)

Synonyms: HUPF1 Protein, NORF1 Protein, RENT1 Protein, pNORF1 Protein, smg-2 Protein, B430202H16Rik Protein, PNORF-1 Protein, Rent1 Protein, Upflp Protein, rent1 Protein, wu:fi40f07 Protein, wu:fj48a01 Protein, zgc:55472 Protein, Tb05.3C6.50 Protein, AO090012000584 Protein, hupf1 Protein, norf1 Protein, pnorf1 Protein, upf1 Protein, UPF1, RNA helicase and ATPase Protein, UPF1 regulator of nonsense transcripts homolog (yeast) Protein, upf1 regulator of nonsense transcripts homolog (yeast) Protein, regulator of nonsense transcripts 1 Protein, Regulator of nonsense transcripts 1 Protein, UPF1 regulator of nonsense transcripts homolog S homeolog Protein, UPF1 Protein, Upf1 Protein, upf1 Protein, Tc00.1047053511317.30 Protein, Tb927.5.2140 Protein, TVAG_453890 Protein, TVAG_237840 Protein, AOR_1_1018194 Protein, HPB8_739 Protein, smg-2 Protein, upf1.S Protein

Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.

Molecular Weight: 122.9 kDa

NCBI Accession: NP_002902

Pathways: SARS-CoV-2 Protein Interactome