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USP7 Protein (Myc-DYKDDDDK Tag)

USP7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735144
  • Target See all USP7 Proteins
    USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This USP7 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human USP7 / HAUSP protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product USP7 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
    Alternative Name
    Usp7,hausp (USP7 Products)
    Synonyms
    CG1490 Protein, Dmel\\CG1490 Protein, USP7 Protein, 2210010O09Rik Protein, AA409944 Protein, AA617399 Protein, AU019296 Protein, AW548146 Protein, C80752 Protein, Hausp Protein, HAUSP Protein, TEF1 Protein, UBP Protein, Ubiquitin-specific protease 7 Protein, ubiquitin carboxyl-terminal hydrolase 7 Protein, ubiquitin specific peptidase 7 Protein, Usp7 Protein, LOC100201254 Protein, USP7 Protein
    Background
    The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
    Molecular Weight
    128.1 kDa
    NCBI Accession
    NP_003461
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