VAC14 Protein (Myc-DYKDDDDK Tag)
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- Target See all VAC14 Proteins
- VAC14 (Vac14 Homolog (VAC14))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VAC14 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human VAC14 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VAC14 Protein
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Vac14 Homolog (VAC14) (AA 714-782) protein (GST tag)
VAC14 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Vac14 Homolog (VAC14) (AA 1-782) protein (GST tag)VAC14 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Vac14 Homolog (VAC14) (AA 1-782) protein (Strep Tag)Crystallography grade VAC14 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- VAC14 (Vac14 Homolog (VAC14))
- Alternative Name
- Vac14 (VAC14 Products)
- Synonyms
- ArPIKfyve Protein, TAX1BP2 Protein, TRX Protein, AA959718 Protein, BC032215 Protein, D8Wsu151e Protein, Tax1bp2 Protein, Trx Protein, ingls Protein, Vac14 homolog L homeolog Protein, Vac14, PIKFYVE complex component Protein, Vac14 homolog (S. cerevisiae) Protein, vac14.L Protein, VAC14 Protein, Vac14 Protein
- Background
- The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]
- Molecular Weight
- 87.8 kDa
- NCBI Accession
- NP_060522
- Pathways
- Inositol Metabolic Process
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