WWOX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735647

Product Details

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This WWOX protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human WWOX / FOR (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Alternative Name: Wwox,for (WWOX Products)

Synonyms: CG7221 Protein, DmWWOX Protein, Dmel\\CG7221 Protein, anon-EST:Posey177 Protein, GB11795 Protein, WWOX Protein, D16S432E Protein, FOR Protein, FRA16D Protein, HHCMA56 Protein, PRO0128 Protein, SDR41C1 Protein, WOX1 Protein, zgc:55975 Protein, 5330426P09Rik Protein, 9030416C10Rik Protein, WW domain containing oxidoreductase Protein, WW domain-containing oxidoreductase Protein, Wwox Protein, LOC411815 Protein, WWOX Protein, CpipJ_CPIJ004939 Protein, MCYG_01584 Protein, VDBG_05631 Protein, VDBG_01326 Protein, VDBG_06753 Protein, Tsp_03967 Protein, LOC100284583 Protein, wwox Protein

Background: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Molecular Weight: 46.5 kDa

NCBI Accession: NP_057457