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DPH3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DPH3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735809
  • Target See all DPH3 Proteins
    DPH3 (DPH3, KTI11 Homolog (DPH3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DPH3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ZCSL2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DPH3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DPH3 (DPH3, KTI11 Homolog (DPH3))
    Alternative Name
    Zcsl2 (DPH3 Products)
    Synonyms
    DELGIP Protein, DELGIP1 Protein, DESR1 Protein, DPH3A Protein, KTI11 Protein, ZCSL2 Protein, 2610018L09Rik Protein, 5730511P15Rik Protein, AL022916 Protein, AV083614 Protein, DelgipP1 Protein, Desr1 Protein, Zcsl2 Protein, diphthamide biosynthesis 3 Protein, diphthamine biosynthesis 3 Protein, DPH3 Protein, Dph3 Protein
    Background
    This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.
    Molecular Weight
    9.1 kDa
    NCBI Accession
    NP_996662
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