GFI1 Protein (His tag)
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- Target See all GFI1 Proteins
- GFI1 (Growth Factor Independent 1 (GFI1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GFI1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ZNF163 (full length, N-term HIS tag, transcript variant 3) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GFI1 Protein
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Growth Factor Independent 1 (GFI1) (AA 1-91) protein (GST tag)
GFI1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Growth Factor Independent 1 (GFI1) (AA 1-422) protein (Strep Tag)Crystallography grade GFI1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Growth Factor Independent 1 (GFI1) (AA 1-423) protein (Strep Tag)Crystallography grade GFI1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Growth Factor Independent 1 (GFI1) protein (His tag)GFI1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GFI1 (Growth Factor Independent 1 (GFI1))
- Alternative Name
- Znf163 (GFI1 Products)
- Synonyms
- AW495828 Protein, Gfi-1 Protein, Pal-1 Protein, Pal1 Protein, GFI1 Protein, GFI-1 Protein, GFI1A Protein, SCN2 Protein, ZNF163 Protein, growth factor independent 1 Protein, growth factor independent 1 transcriptional repressor Protein, Gfi1 Protein, GFI1 Protein
- Background
- This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
- Molecular Weight
- 45.1 kDa
- NCBI Accession
- NP_001120688
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