IKZF3 Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2736142

Product Details

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 5

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IKZF3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ZNFN1A3 (IKZF3, Aiolos) (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Alternative Name: Znfn1a3 (Ikzf3, Aiolos) (IKZF3 Products)

Synonyms: AIO Protein, AIOLOS Protein, ZNFN1A3 Protein, aio Protein, aiolos Protein, znfn1a3 Protein, IKZF3 Protein, 5830411O07Rik Protein, Aiolos Protein, Zfpn1a3 Protein, Znfn1a3 Protein, IKAROS family zinc finger 3 Protein, IKAROS family zinc finger 3 L homeolog Protein, IKZF3 Protein, ikzf3.L Protein, Ikzf3 Protein

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Molecular Weight: 46.8 kDa

NCBI Accession: NP_899054