CLEC7A Protein (AA 72-244) (Fc Tag)
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- Target See all CLEC7A Proteins
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 72-244
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC7A protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse dectin-1 (aa 72-244) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product CLEC7A Protein
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C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 71-244) protein (Fc Tag)
CLEC7A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 66-201) protein (Fc Tag)CLEC7A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-77) protein (GST tag)CLEC7A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Type Lectin Domain Family 7, Member A (CLEC7A) protein (His tag)CLEC7A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 66-247) protein (His tag)Crystallography grade CLEC7A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 71-244) protein (His tag)Crystallography grade CLEC7A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-247) protein (Strep Tag)Crystallography grade CLEC7A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-244) protein (Strep Tag)Crystallography grade CLEC7A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Alternative Name
- Dectin-1 (CLEC7A Products)
- Synonyms
- CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
- Background
- Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
- Molecular Weight
- ~56kDa (SDS-PAGE)
- UniProt
- Q6QLQ4
- Pathways
- Activation of Innate immune Response
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