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KAT2A Protein (His tag)

KAT2A Origin: Human Host: Insect cells (Sf21) Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN2745695
  • Target See all KAT2A Proteins
    KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    Insect cells (Sf21)
    Purification tag / Conjugate
    This KAT2A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Cross-Reactivity
    Human
    Characteristics
    Human GCN5 is fused to a His-tag.
    Purity
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product KAT2A Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    ~200-300ng are required for standard HAT assay.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50 mM imidazole and 10 % glycerol.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Short Term Storage: -20°C
    Long Term Storage: -80°C
    Stable for at least 6 months after receipt when stored at -80°C.
    Expiry Date
    6 months
  • Target
    KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
    Alternative Name
    GCN5 (KAT2A Products)
    Synonyms
    KAT2A Protein, GCN5L2 Protein, GCN5 Protein, PCAF-b Protein, hGCN5 Protein, 1110051E14Rik Protein, AW212720 Protein, Gcn5 Protein, Gcn5l2 Protein, mmGCN5 Protein, K(lysine) acetyltransferase 2A Protein, lysine acetyltransferase 2A Protein, histone acetyltransferase KAT2A Protein, ras-related protein Rab-5C Protein, KAT2A Protein, LOC100176452 Protein, LOC100597293 Protein, Kat2a Protein
    Background
    GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.
    UniProt
    Q92830
    Pathways
    Chromatin Binding, Tube Formation
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