PARP3 Protein (HA tag,His tag)
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- Target See all PARP3 Proteins
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Insect cells (Sf21)
- Purification tag / Conjugate
- This PARP3 protein is labelled with HA tag,His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag.
- Purity
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product PARP3 Protein
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Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (AA 1-533) protein (GST tag)
PARP3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (AA 1-533) protein (Strep Tag)Crystallography grade PARP3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PARP3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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>10U/mg protein (only monoADP-ribosyl transferase activity).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride and 50 mM imidazole, 0.2 % NP-40 and 10 % glycerol.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Expiry Date
- 6 months
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- Target
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- Alternative Name
- PARP-3 [ARTD3] (PARP3 Products)
- Synonyms
- ADPRT-3 Protein, PARP-3 Protein, PM38 Protein, Adprtl3 Protein, fj17c06 Protein, wu:fj17c06 Protein, zgc:66157 Protein, PARP3 Protein, parp3 Protein, ADPRT3 Protein, ADPRTL2 Protein, ADPRTL3 Protein, ARTD3 Protein, IRT1 Protein, PADPRT-3 Protein, A930002C11Rik Protein, AW990611 Protein, Adprt3 Protein, pADPRT-3 Protein, seed maturation protein PM38 Protein, poly (ADP-ribose) polymerase family, member 3 Protein, poly(ADP-ribose) polymerase family member 3 Protein, poly(ADP-ribose) polymerase family member 3 L homeolog Protein, PARP3 Protein, parp3 Protein, parp3.L Protein, Parp3 Protein
- Background
- PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- UniProt
- Q9Y6F1
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