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IL1RAP Protein (AA 21-359) (Fc Tag)

IL1RAP Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2749237
  • Target See all IL1RAP Proteins
    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-359
    Origin
    • 20
    • 5
    • 1
    Human
    Source
    • 13
    • 5
    • 4
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL1RAP protein is labelled with Fc Tag.
    Sequence
    AA 21-359
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 65.7 kDa. The protein migrates as 75-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL1RAP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
    Alternative Name
    IL-1 RAcP (IL1RAP Products)
    Synonyms
    IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein
    Background
    Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
    Molecular Weight
    65.7 kDa
    UniProt
    Q9NPH3
    Pathways
    NF-kappaB Signaling, Growth Factor Binding
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