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CCL16 Protein

CCL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant >97 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2829998
  • Target See all CCL16 Proteins
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    Human
    Source
    • 7
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func)
    Sequence
    QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
    Characteristics
    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/mL.
    Purity
    >97 % as determined by SDS-PAGE and HPLC.
    Sterility
    0.2 μm filtered
    Top Product
    Discover our top product CCL16 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    Alternative Name
    CCL16 (CCL16 Products)
    Synonyms
    CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
    Background
    Relevance: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
    Synonyms: Chemokine CC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine
    Molecular Weight
    11.2 kDa
    UniProt
    O15467
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