Vaccinia Related Kinase 1 (VRK1) (full length) (Active) protein (GST tag)

Details for Product No. ABIN2959586, Supplier: Log in to see
Protein Name
  • vrk1
  • MGC64390
  • MGC75762
  • VRK1
  • PCH1
  • PCH1A
  • 51PK
  • wu:fe16f06
  • zgc:56266
  • vaccinia related kinase 1
  • Protein VRK-1
  • vrk1
  • VRK1
  • LOC100340357
  • vrk-1
  • Vrk1
Protein Characteristics
full length
8
3
1
1
1
1
1
Origin
Human
13
1
1
Source
Baculovirus infected Insect Cells
5
3
2
2
2
1
Protein Type
Recombinant
Biological Activity
Active
Purification tag / Conjugate
GST tag
Application
Functional Studies (Func), Western Blotting (WB)
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Characteristics Recombinant full-length human VRK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Background VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. VRK1 is widely expressed in human tissues and actively dividing cells, such as those in testis, leukocytes, fetal liver and carcinomas. VRK1 regulate cell proliferation and phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. The spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene.
Synonyms: MGC117401, MGC138280, MGC142070
Molecular Weight ~71 kDa
NCBI Accession NM_003384
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Handling Advice For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage -80 °C
Storage Comment Store product at -70 °C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
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