P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Active) Protein

Details for Product No. ABIN411934, Supplier: Log in to see
Protein Name
  • PAK5
  • pak5
  • 2900083L08Rik
  • 6430627N20
  • Pak5
  • PAK-5
  • PAK-7
  • p21 (RAC1) activated kinase 5
  • p21 (RAC1) activated kinase 5 L homeolog
  • p21 protein (Cdc42/Rac)-activated kinase 7
  • p21 (RAC1) activated kinase 7
  • PAK5
  • pak5.L
  • Pak7
Origin
Human
10
1
1
Source
Baculovirus infected Insect Cells
5
3
1
1
1
1
Protein Type
Recombinant
Biological Activity
Active
Application
Functional Studies (Func), SDS-PAGE (SDS), Western Blotting (WB)
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Purpose >75% Pure active Recombinant PAK7.
Characteristics Protein Source: Baculovirus (Sf9 insect cells)
Purity SDS-PAGE: ≥75 %
Background The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.
Alternate Names: PAK7, Serine/threonine-protein kinase PAK 7
Molecular Weight 130.0 kDa
Gene ID 57144
UniProt Q9P286
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Activity Specification: 55 nmol phosphate incorporated into the Akt substrate peptide (CKRPRAASFAE) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 μM ATP (0.83 μCi/assay).

Restrictions For Research Use only
Format Liquid
Concentration 0.1 μg/μL
Buffer Recombinant protein in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25 % glycerol).
Preservative Dithiothreitol (DTT)
Precaution of Use This product contains dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Centrifuge the vial prior to opening.
Storage -80 °C
Storage Comment -80°C
Expiry Date 12 months
Supplier Images
SDS-PAGE (SDS) image for P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Active) protein (ABIN411934) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Active) protein
Activity Assay (AcA) image for P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Active) protein (ABIN411934) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Active) protein (Image 2)
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