4-1BB Receptor Protein

Name: 4-1BB Receptor

Protein Type: Recombinant

Source: Escherichia Coli (E. coli)

Origin (Gene): Human

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Catalog no.: ABIN412987

Additional Information

Characteristics: Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 μ g for both 4-1BBL and 4-1BBR.

Description: Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Recombinant human 4-1BBR is a 17.7 kDa protein containing 167 amino acid residues of extracellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).

Molecular Weight: 17.7 kDa

Application Details

Purity: >95% by SDS-PAGE analyses Endotoxin level is <0.1 ng per μ g.

Buffer: Lyophilized from 0.3X PBS

Storage: The lyophilized protein is best-stored desiccated below 0 °C. Reconstituted human 4- 1BBR should be stored in working aliquots at -20 °C. Reconstitution: We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 1 week or –20 °C for future use.

Restrictions: For Research Use only