Apolipoprotein A-I (APOA1) Protein

Details for Product No. ABIN413012
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Protein Name
Synonyms APOA1, MGC64335, MGC89745, apoa-i, ApoA-I, LOC100136573, apoa1, Alp-1, Apoa-1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2, Sep2, apoA-I, Apo-AI, ApoAI, apoa, cb49, wu:fb33f01, zgc:103718
Origin
Human
(41), (10), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Source
Escherichia coli (E. coli)
(23), (10), (9), (5), (4), (2), (2), (2)
Protein Type Recombinant
Application
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 2 references available
Quantity 100 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN413012
209.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Purity > 97 % by SDS-PAGE and HPLC analysis
Sterility Sterile filtered
Endotoxin Level < 0.1 ng/μg
Alternative Name ApoA-1
Background ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the \\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\
Molecular Weight 28.2 kDa
Gene ID 335
NCBI Accession NM_000039
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in H2O to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers and store at 4 °C for 1 week or -20 °C for future use.
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Barlic, Zhu, Murphy: "Atherogenic lipids induce high-density lipoprotein uptake and cholesterol efflux in human macrophages by up-regulating transmembrane chemokine CXCL16 without engaging CXCL16-dependent cell adhesion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7928-36, 2009 (PubMed).

Saeed, Otsuka, Polavarapu et al.: "Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 2, pp. 299-307, 2012 (PubMed).

Validation Images
back to top