D4-GDI Protein

Name: D4-GDI

Synonyms: ARHGDIB

Protein Type: Recombinant

Source: Escherichia Coli (E. coli)

Origin (Gene): Human

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Catalog no.: ABIN413175

Additional Information

Description: D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins, consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.

Molecular Weight: 54 kDa

Application Details

Purity: > 90% as determined by SDS-PAGE and HPLC. ENDOTOXIN: Endotoxin level is less than 0.1 ng/mg of D4-GDI PHYSICAL

Buffer: 100µg/ml in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% Glycerol.

Storage: Stable at –20 °C or –80 ο C. Stable for 6-12 months. Avoid freeze-thaw cycles.

Restrictions: For Research Use only