Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (Active) Protein

Details for Product No. ABIN413326
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Protein Name
Synonyms GMCSF, Csfgm, Gm-CSf, MGI-IGM, Gmcsf, Gm-csf, CSF, GM-CSF, CSF2
Origin
Human
(124), (34), (21), (13), (10), (4), (3), (2), (1), (1), (1)
Source
Escherichia coli (E. coli)
(120), (20), (9), (8), (6), (6), (4), (2), (2), (2)
Protein Type Recombinant
Biological Activity Active
Application
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 3 references available
Catalog no. ABIN413326
Quantity 10 µg
Price
209.00 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Characteristics Biological activity: less than 0.1 ng/mL, The ED50 determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is less than 0.1 ng/mL, corresponding to a specific activity of more than1 x 10^7 U/mg.
Purity > 98 % by SDS-PAGE and HPLC analysis
Endotoxin Level < 0.1 ng/μg
Alternative Name GM-CSF
Background Human GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and eosinophils. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein containing 128 amino acid residues.
Synonyms: human GM-CSF, GM-CSF,GMCSF, GM CSF, h-GM-CSF, rh-GM-CSF, recombinant human GM-CSF, recombinant GM-CSF, Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Molecular Weight 14.6 kDa
Gene ID 1437
UniProt P04141
Research Area Immunology, Innate Immunity, Cytokines, Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in H2O to a concentration of 0.1-1.0 µg/µL. This solution can then be diluted into other aqueous buffers or stored at 4 °C for 1 week or -20 °C for future use.
Buffer 10 mM Sodium Citrate, pH 3.5
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Santegoets, Bontkes, Stam et al.: "Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4540-9, 2008 (PubMed).

van de Ven, Scheffer, Reurs et al.: "A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration." in: Blood, Vol. 112, Issue 6, pp. 2353-9, 2008 (PubMed).

Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).

Hosts (120), (20), (9), (8), (6), (6), (4), (2), (2), (2)
Reactivities (124), (34), (21), (13), (10), (4), (3), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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