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Details for Product No. ABIN413326

Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (Active) Protein

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Protein Name
Synonyms GMCSF, Csfgm, Gm-CSf, MGI-IGM, Gmcsf, Gm-csf, CSF, GM-CSF, CSF2
Origin
»Alternatives Human
Source
»Alternatives Escherichia coli (E. coli)
Protein Type Recombinant
Biological Activity Active
Application
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 3 references available
Catalog no. ABIN413326
Quantity 10 µg
Price
209.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Characteristics Biological activity: less than 0.1 ng/mL, The ED50 determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is less than 0.1 ng/mL, corresponding to a specific activity of more than1 x 10^7 U/mg.
Purity > 98 % by SDS-PAGE and HPLC analysis
Endotoxin Level < 0.1 ng/μg
Alternative Name GM-CSF
Background Human GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and eosinophils. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein containing 128 amino acid residues.
Synonyms: human GM-CSF, GM-CSF,GMCSF, GM CSF, h-GM-CSF, rh-GM-CSF, recombinant human GM-CSF, recombinant GM-CSF, Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Molecular Weight 14.6 kDa
Gene ID 1437
UniProt P04141
Research Area Immunology, Innate Immunity, Cytokines, Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in H2O to a concentration of 0.1-1.0 µg/µL. This solution can then be diluted into other aqueous buffers or stored at 4 °C for 1 week or -20 °C for future use.
Buffer 10 mM Sodium Citrate, pH 3.5
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Santegoets, Bontkes, Stam et al.: "Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4540-9, 2008 (PubMed).

van de Ven, Scheffer, Reurs et al.: "A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration." in: Blood, Vol. 112, Issue 6, pp. 2353-9, 2008 (PubMed).

Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).

Alternatives for antigen "Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)", type "Proteins"
Hosts (112), (15), (9), (8), (6), (6), (4), (2), (2)
Reactivities (110), (34), (21), (13), (10), (4), (3), (2), (1), (1), (1), (1)
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