You are viewing an incomplete version of our website. Please click to reload the website as full version.

Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (Active) Protein

Details for Product No. ABIN413328, Supplier: Log in to see
Protein Name
Origin
Human
118
43
23
8
7
5
3
3
1
1
1
1
1
1
Source
Escherichia coli (E. coli)
131
12
10
8
5
5
3
3
3
3
2
2
1
1
1
1
Protein Type
Recombinant
Biological Activity
Active
Application
High Pressure Liquid Chromatography (HPLC), SDS-PAGE (SDS)
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Characteristics 14.6 kDa
Biological Activity: The ED₅₀ determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <0.1 ng/mL, corresponding to a specific activity of >1 x 10⁷ units/mg.
Purity ≥98 %
Endotoxin Level <0.1 ng/μg
Background Human GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and eosinophils. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein containing 128 amino acid residues.
Synonyms: human GM-CSF, GM-CSF,GMCSF, GM CSF, h-GM-CSF, rh-GM-CSF, recombinant human GM-CSF, recombinant GM-CSF, Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Molecular Weight 14.6 kDa
Gene ID 1437
UniProt P04141
Research Area Immunology, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in H₂O to a concentration of 0.1-1.0 μg/μl. This solution can then be diluted into other aqueous buffers or stored at 4 °C for 1 week or -20 °C for future use.
Buffer Lyophilized from 10 mM Sodium Citrate, pH 3.5
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).

van de Ven, Scheffer, Reurs et al.: "A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration." in: Blood, Vol. 112, Issue 6, pp. 2353-9, 2008 (PubMed).

Santegoets, Bontkes, Stam et al.: "Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4540-9, 2008 (PubMed).