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Details for Product No. ABIN413478

Interleukin 1, beta (IL1B) (Active) Protein

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Protein Name
Synonyms IL-1, IL1F2, IL1-BETA, IL-1BETA, IL1beta, IL-1B, IL-1beta, Il-1b, IL1B, il1-b, zgc:111873
»Alternatives Human
»Alternatives Escherichia coli (E. coli)
Protein Type Recombinant
Biological Activity Active
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 1 reference available
Catalog no. ABIN413478
Quantity 10 µg
198.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Characteristics Biological activity: less than 0.1 ng/mL The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes is less than 0.1 ng/mL, corresponding to a specific activity of more than1 x 10^7 U/mg.
Purity > 98 % by SDS-PAGE and HPLC analysis
Endotoxin Level < 0.1 ng/μg
Alternative Name IL-1 beta
Background IL-1beta is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses including the activation of B and T cells. Recombinant human IL-1beta is a 17.0 kDa protein containing 153 amino acid residues.
Synonyms: Human IL-1beta, IL-1beta, IL1beta, IL 1beta, h- IL-1beta, rh-IL-1beta, recombinant human IL-1beta, recombinant IL-1beta, IL, interluekin, Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Molecular Weight 17.0 kDa
Gene ID 3553
UniProt P01584
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer, Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution We recommend a quick spin followed by reconstitution in H2O to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers and stored at 4 °C for 1 week or stored at -20 °C for future use.
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Kahlenberg, Thacker, Berthier et al.: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, 2011 (PubMed).

Alternatives for antigen "Interleukin 1, beta (IL1B)", type "Proteins"
Hosts (105), (11), (2), (1)
Reactivities (62), (44), (14), (11), (10), (4), (4), (3), (2), (1), (1), (1), (1), (1)