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Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (Active) Protein

Details for Product No. ABIN413516, Supplier: Login to see
Protein Name
  • BPA
  • Csfmu
  • HCGF
  • Il-3
  • MCGF
  • PSF
  • IL-3
  • MULTI-CSF
Origin
Human
80
36
17
7
2
1
1
1
1
1
Source
Escherichia coli (E. coli)
99
7
4
4
2
2
2
2
2
1
1
1
1
1
1
1
Protein Type
Recombinant
Biological Activity
Active
Application
High Pressure Liquid Chromatography (HPLC), SDS-PAGE (SDS)
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Characteristics 15.0 kDa
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.1 ng/mL, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg
Purity ≥98 %
Sterility Sterile filtered
Endotoxin Level <0.1 ng/μg
Background IL-3 is a species-specific colony-stimulating factor that stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Recombinant human IL-3 is a 15.0 kDa protein containing 133 amino acid residues
Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399, MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399.
Molecular Weight 15.0 kDa
Gene ID 3562
UniProt P08700
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Comment

physical form description: Sterile filtered and lyophilized with no additives

Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in H₂O to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (Active) Protein (ABIN413516) Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (Active) protein
Product cited in: Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).