KIT Ligand (KITLG) (Active) Protein

Name: KIT Ligand (KITLG)

Synonyms: SF, MGF, SCF, FPH2, KL-1, Kitl, SHEP7, DKFZp686F2250, kitlg, MGC52814, KITLG, Xsl, mgf, scf, kitl, kl-1, Xkl-1, Xsl-1, Xsl-2, steel

Protein Type: Recombinant

Biological Activity: Active

Source: Escherichia Coli (E. coli)

Origin (Gene): Human

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Catalog no.: ABIN413772

Additional Information

Gene ID: 4254

UniProt: P21583

Endotoxin Level: <0.1 ng/µg

Description: Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures. Human SCF is an 18.4 kDa protein containing 165 amino acid residues.
Synonyms: Human SCF, SCF, h-SCF, rh-SCF, recombinant human SCF, recombinant SCF, Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250.

Characteristics: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 2 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg.

Molecular Weight: 18.4 kDa

Application Details

Handling Advice: Centrifuge the vial prior to opening.

Purity: >98% by SDS-PAGE and HPLC analyses Endotoxin level is <0.1 ng/ μ g of SCF.

Buffer: lyophilized from 10 mM Acetic Acids

Storage: -20°C.
Stability: 12 months

Restrictions: For Research Use only

Publications

Product: Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).