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KIT Ligand (KITLG) (Active) Protein

Details for Product No. ABIN413771, Supplier: Log in to see
Protein Name
  • 710-712
  • blz
  • Clo
  • Con
  • contrasted
  • CSF
  • FPH2
  • Gb
  • Kitl
  • kitl
  • KITL
  • Kitlg
  • KITLG
  • KL-1
  • kl-1
  • Mgf
  • MGF
  • mgf
  • scf
  • SCF
  • SF
  • SHEP7
  • Sl
  • SLF
  • steel
  • Xkl-1
  • Xsl
  • Xsl-1
  • Xsl-2
Origin
Human
75
43
19
3
1
1
1
1
1
1
1
1
Source
Escherichia coli (E. coli)
90
9
8
6
5
3
2
2
2
2
1
1
1
1
1
1
Protein Type
Recombinant
Biological Activity
Active
Application
High Pressure Liquid Chromatography (HPLC), SDS-PAGE (SDS)
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Characteristics Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 2 ng/mL, corresponding to a specific activity of >5 x 10⁵ units/mg.
Purity ≥98 %
Endotoxin Level <0.1 ng/μg
Background Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures. Human SCF is an 18.4 kDa protein containing 165 amino acid residues.
Synonyms: Human SCF, SCF, h-SCF, rh-SCF, recombinant human SCF, recombinant SCF, Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250.
Molecular Weight 18.4 kDa
Gene ID 4254
UniProt P21583
Research Area Embryogenesis, Embryonic stem cells, Innate Immunity, Cytokines
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute the lyophilized human SCF in sterile H₂O to a concentration of 0.1-1 mg/mL. The solutions can then be diluted into other aqueous buffers and stored at 4 °C for 1 week or -20 °C for future use.
Buffer Lyophilized from 10 mM Acetic Acid
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for KIT Ligand (KITLG) (Active) Protein (ABIN413771) KIT Ligand (KITLG) (Active) protein
Product cited in: Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011