KIT Ligand (KITLG) (Active) Protein

Details for Product No. ABIN413772
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Protein Name
Synonyms Xkl-1, Xsl, Xsl-1, Xsl-2, steel, KITLG, SCF, kitl, kl-1, mgf, scf, FPH2, KL-1, Kitl, MGF, SF, SHEP7, Clo, Con, Gb, Kitlg, Mgf, SLF, Sl, blz, contrasted, 710-712, CSF, KITL
Origin
Human
(90), (33), (18), (3), (1), (1), (1)
Source
Escherichia coli (E. coli)
(81), (9), (8), (7), (5), (4), (4), (3), (3), (2), (2), (1)
Protein Type Recombinant
Biological Activity Active
Application
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN413772
544.50 $
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  • +1 888 205 9894 (TF)
Characteristics Biological activity: less than 2 ng/mL The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is less than 2 ng/mL, corresponding to a specific activity of more than5 x 10^5 U/mg.
Purity > 98 % by SDS-PAGE and HPLC analysis
Endotoxin Level < 0.1 ng/μg
Alternative Name SCF
Background Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures. Human SCF is an 18.4 kDa protein containing 165 amino acid residues.
Synonyms: Human SCF, SCF, h-SCF, rh-SCF, recombinant human SCF, recombinant SCF, Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250.
Molecular Weight 18.4 kDa
Gene ID 4254
UniProt P21583
Research Area Embryogenesis, Embryonic stem cells, Innate Immunity, Cytokines, Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute the lyophilized human SCF in sterile H2O to a concentration of 0.1-1 mg/mL. The solutions can then be diluted into other aqueous buffers and stored at 4 °C for 1 week or -20 °C for future use.
Buffer 10 mM Acetic Acids
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Kinzfogl, Hangoc, Broxmeyer: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, 2011 (PubMed).

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