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Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (Active) Protein

Details for Product No. ABIN413778
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Protein Name
Synonyms IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, Pbsf, Scyb12, Sdf1, Tlsf, Tpar1, sdf-1, sdf1, xSDF-1, SDF-1, sdf1a, a-sdf1a
Origin
Human
(44), (22), (13), (11), (2), (1), (1)
Source
Escherichia coli (E. coli)
(69), (4), (2)
Protein Type Recombinant
Biological Activity Active
Application
Western Blotting (WB), ELISA, Functional Studies (Func)
Pubmed 4 references available
Quantity 10 µg
Options
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Catalog No. ABIN413778
209.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Characteristics Biological activity: 20-80 ng/mL Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20-80 ng/mL.
Purity > 98 % by SDS-PAGE and HPLC analysis
Sterility Sterile filtered
Endotoxin Level < 0.1 ng/μg
Alternative Name SDF-1 alpha/cxcl12
Background Human Stromal Cell-Derived Factor-1alpha (SDF-1alpha) is a recently discovered protein belonging to the alpha-chemokine (C-X-C) family of cytokines. Human SDF-1alpha is an 8.0 kDa protein containing 68 AA residues with N-terminus His-tag
Synonyms: Human SDF-1alpha, h-SDF-1alpha,SDF-1alpha, SDF1alpha,SDF 1alpha, rh-SDF-1alpha, recombinant human SDF-1alpha, recombinant SDF-1alpha, SDF, SDF-1, CXCL12, Pre-B cell growth-stimulating factor, PBSF, hIRH, chemokine (C-X-C motif) ligand 12, SDF1, SDF1A, TPAR1, SCYB12, SDF-1a, TLSF-a.
Molecular Weight 8.0 kDa
Gene ID 6387
UniProt P48061
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitution in H2O to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers or stored at 4 °C for 1 week or -20 °C for future use.
Buffer Lyophilized with no additives
Preservative Without preservative
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Basu, Broxmeyer: "Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12." in: Blood, Vol. 106, Issue 2, pp. 485-93, 2005 (PubMed).

Miwa, Mizokami, Keller et al.: "The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer." in: Cancer research, Vol. 65, Issue 19, pp. 8818-25, 2005 (PubMed).

Basu, Ray, Atkinson et al.: "Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 5, pp. 3075-85, 2007 (PubMed).

di Tomaso, Snuderl, Kamoun et al.: "Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape." in: Cancer research, Vol. 71, Issue 1, pp. 19-28, 2011 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN413778
209.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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