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ICAM2 Protein (AA 25-223) (His tag)

ICAM2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN4370385
  • Target See all ICAM2 Proteins
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-223
    Origin
    • 16
    • 7
    • 2
    • 1
    • 1
    Human
    Source
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This ICAM2 protein is labelled with His tag.
    Purpose
    Recombinant Human Intercellular Adhesion Molecule 2/ICAM-2/CD102 (C-6His)
    Sequence
    KVFEVHVRPK KLAVEPKGSL EVNCSTTCNQ PEVGGLETSL DKILLDEQAQ WKHYLVSNIS HDTVLQCHFT CSGKQESMNS NVSVYQPPRQ VILTLQPTLV AVGKSFTIEC RVPTVEPLDS LTLFLFRGNE TLHYETFGKA APAPQEATAT FNSTADREDG HRNFSCLAVL DLMSRGGNIF HKHSAPKMLE IYEPVSDSQV DHHHHHH
    Characteristics
    Recombinant Human Intercellular Adhesion Molecule 2/ICAM-2 produced by transfected human cells is a secreted protein with sequence (Lys25-Gln223) of Human ICAM2 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ICAM2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM CaCl2, 2 mM MgCl2, 5 % Threhalose, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Alternative Name
    cd102 (ICAM2 Products)
    Synonyms
    ICAM2 Protein, CD102 Protein, Icam-2 Protein, Ly-60 Protein, intercellular adhesion molecule 2 Protein, LOC506088 Protein, ICAM2 Protein, LOC616254 Protein, LOC100140873 Protein, Icam2 Protein
    Sub Type
    Fusionprotein
    Background
    ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
    Alternative Names: Intercellular Adhesion Molecule 2, ICAM-2, CD102, ICAM2
    Molecular Weight
    23.13 kDa
    UniProt
    P13598
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