Fibrinogen protein (FITC)

Details for Product No. ABIN490990
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Protein Name
Synonyms fib2, MGC53620, fibrinogen, sb:cb892, wu:fa55c12, wu:fb20e08, wu:fb59b03, wu:fi39d04, zgc:92117
Origin
Human
(10), (5), (3), (3), (3), (3), (3), (2)
Source
Human
(9), (4), (2), (2), (2), (2), (2), (2)
Protein Type Native
Purification tag / Conjugate
FITC
Pubmed 1 reference available
Quantity 10 mg
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Catalog No. ABIN490990
104.50 $
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Characteristics Human fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh human plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw at 37 °C without agitation until completely liquid, then gently mix before use.
Purification Chromatographically purified
Purity > 95 % by SDS-PAGE
Gene ID 2243, 2244, 2266
UniProt P02671
Research Area Cardiovascular, Atherosclerosis, Extracellular Matrix, Coagulation
Restrictions For Research Use only
Format Frozen
Concentration 10 mg/mL
Buffer 20 mM Sodium Citrate-HCl, pH 7.4
Handling Advice Protect from light
Storage -80 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.

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