Plasminogen Activator, Tissue (PLAT) protein (FITC)

Details for Product No. ABIN491026
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Protein Name
Synonyms tpa, Plat, T-PA, TPA, AU020998, AW212668, D8Ertd2e, tPA, PATISS
Origin
Human
(33), (17), (5), (2), (2)
Source
CHO
(14), (8), (6), (4), (3), (1), (1)
Protein Type Recombinant
Purification tag / Conjugate
FITC
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN491026
478.50 $
Plus shipping costs $45.00 and if applicable $26.40 dry ice

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  • +1 404 474 4654
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Characteristics Fluorescein labeled tPA, > 85 % single chain. 100 % complex formation with PAI-1.
Purity >95% by SDS-PAGE analysis
Alternative Name Tissue Plasminogen Activator (tPA)
Molecular Weight 70000 Da
Gene ID 5327
UniProt P00750
Research Area Coagulation
Restrictions For Research Use only
Format Frozen
Concentration 2.0 mg/mL
Buffer 0.4M HEPES, 0.1M NaCl, pH 7.4
Handling Advice Protect from light
Storage -80 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.

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