Plasminogen Activator, Tissue (PLAT) protein (FITC)

Details for Product No. ABIN491026
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Protein Name
Synonyms T-PA, TPA, AU020998, AW212668, D8Ertd2e, tPA, PATISS, tpa, Plat
(33), (16), (4), (2), (2), (1)
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(5), (4), (4), (4)
Purification tag / Conjugate
Pubmed 1 reference available
Catalog no. ABIN491026
Quantity 0.1 mg
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Purification Chromatographically purified
Purity >95% by SDS-PAGE
Alternative Name Tissue Plasminogen Activator (tPA)
Background Human tissue plasminogen activator, single chain, FITC labeled. Fluorescein labeled tPA, >85% single chain. 100% complex formation with PAI-1.
Molecular Weight 70000
Gene ID 5327
UniProt P00750
Format Frozen
Concentration Sample concentration 2.0 mg/ml, concentration varies by lot
Buffer 0.4M HEPES, 0.1M NaCl, pH 7.4
Storage -80 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.

Hosts (5), (4), (4), (4)
Reactivities (33), (16), (4), (2), (2), (1)
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