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Plasminogen Activator, Tissue (PLAT) protein (FITC)

Details for Product No. ABIN491026, Supplier: Log in to see
Protein Name
  • tpa
  • Plat
  • T-PA
  • TPA
  • AU020998
  • AW212668
  • D8Ertd2e
  • tPA
  • PATISS
Origin
Human
35
19
5
2
2
Source
CHO
15
14
5
4
3
1
1
1
Protein Type
Recombinant
Purification tag / Conjugate
FITC
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Characteristics Fluorescein labeled tPA, > 85 % single chain. 100 % complex formation with PAI-1.
Purification Chromatographically purified
Purity > 95 % by SDS-PAGE
Gene ID 5327
UniProt P00750
Research Area Coagulation
Restrictions For Research Use only
Format Frozen
Concentration 2.0 mg/mL
Buffer 0.4M HEPES, 0.1M NaCl, pH 7.4
Handling Advice Protect from light
Storage -80 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.