Plasminogen Activator, Urokinase (PLAU) protein (Fluorescein)

Details for Product No. ABIN491028, Supplier: Log in to see
Protein Name
  • PLAU
  • u-PA
  • ATF
  • BDPLT5
  • QPD
  • UPA
  • URK
  • uPA
  • UPAM
  • plasminogen activator, urokinase
  • urokinase-type plasminogen activator
  • PLAU
  • CpipJ_CPIJ002131
  • CpipJ_CPIJ006543
  • CpipJ_CPIJ013396
  • CpipJ_CPIJ013623
  • Plau
Origin
Human
39
7
4
2
2
2
2
1
1
Source
Human
15
11
8
5
5
5
2
1
1
1
Protein Type
Native
Purification tag / Conjugate
This PLAU protein is labelled with Fluorescein.
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Characteristics Fluorescein labeled two-chain urokinase.
Purification Chromatographically purified
Purity > 95 % by SDS-PAGE
Gene ID 5328
UniProt P00749
Pathways Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Restrictions For Research Use only
Format Frozen
Concentration 2.5 mg/mL
Buffer 0.05M Sodium Acetate, 0.1M NaCl, 1 mM EDTA, pH 5.0
Handling Advice Protect from light
Storage -80 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.