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Ac-TVASSSTA Octapeptide Protein
| Name | Ac-TVASSSTA Octapeptide |
| Catalog no. | ABIN491463 |
| Quantity | 5.0 mg |
| Price | 485.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 3 to 10 Business Days |
Additional Information
| Format | Lyophilized |
| Description | Ac-TVASSSTA Octapeptide. Ac-TVASSSTA is an Octapeptide mimic of the N-terminal residues of the reactive center loop of PAI-1 (cf. P14-P7 residues). The Octapeptide inactivates PAI-1 by substituting for strand 4 in beta-sheet A in a manner that competes with formation of the latent species. Insertion of the peptide into beta-sheet A effectively forms a stable complex that converts PAI-1 into a substrate for tissue-type plasminogen activator (tPA) and other target proteinases. The resulting species of PAI-1 is thermodynamically stable and is useful for investigating the role of reactive center loop insertion. Supplied as a lyophilized powder. |
| Molecular Weight | 765 |
Application Details
| Purity | >95% by HPLC |
| Purification | Chromatographically purified |
| Buffer | Salt free |
| Storage | Store at -70°C |
| Research Area | Proteases |
