Elastase, Neutrophil Protein

Name: Elastase, Neutrophil

Synonyms: GE, NE, HLE, HNE, ELA2, PMN-E, Ela2, F430011M15Rik, ELANE, ela2, MGC89201, MGC157260

Origin (Gene): Human

Catalog no.: ABIN491554

Additional Information

Gene ID: 1991

Swiss-Prot: P12277

Format: Frozen

Description: Human Neutrophil Elastase. Chromatographically purified from human leukocytes. The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains. Neutrophils are leukocytes whose primary role is to destroy any foreign particles, either by phagocytosis or by release of bacteriostatic agents. Neutrophils contain high concentrations of the serine proteinase neutrophil elastase that is stored in intracellular vacuoles termed the azurophilic granules. This proteinase is a major protein constituent of neutrophils, comprising around 1-3 pg per neutrophil. Their primary role is to digest any pathogens that the neutrophil has phagocytosed. No detectable amounts of Cathepsin G or MPO. Stability > 1 year at 4 C. Activity >10 u/ml @ 37 C.

Molecular Weight: 29600

Application Details

Concentration: Sample concentration 1.0 mg/ml, concentration varies by lot

Purity: >95% by SDS-PAGE

Purification: Chromatographically purified

Buffer: 0.05M Sodium Acetate, 0.6M NaCl, pH 5.5

Storage: Store at -70°C