alpha-2-Macroglobulin (A2M) Protein

Details for Product No. ABIN491569, Supplier: Log in to see
Protein Name
  • A2M
  • LOC733429
  • LOC100221148
  • LOC100224071
  • endod
  • cpamd5
  • fwp007
  • s863-7
  • a2mb
  • endodermin
  • A2MD
  • CPAMD5
  • FWP007
  • S863-7
  • A2mp
  • A2MAC1
  • A2m1
  • A2maa
  • Mam
  • alpha-2-macroglobulin
  • ovostatin
  • pregnancy-zone protein
  • A2M
  • LOC733429
  • AZL_c00450
  • LOC100221148
  • LOC100224071
  • LOC100349077
  • OVST
  • a2m
  • A2m
  • LOC100353095
  • PZP
Origin
Human
22
8
7
2
1
Source
Human
17
14
2
1
1
1
1
1
Protein Type
Native
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Characteristics A major serum protein found at concentrations of 240 mg per 100 mLin men and 290 mg per 100 mLin women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a proteinase inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Purification Chromatographically purified
Purity > 95 % by SDS-PAGE
Gene ID 2
UniProt P01023
Research Area Serum/Plasma Proteins
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add deionized water to original volume, aliquot and freeze unused portion.
Buffer 0.03M Sodium Phosphate, 0.1M Glycine, pH 7.0
Storage -80 °C
Supplier Images
SDS-PAGE (SDS) image for alpha-2-Macroglobulin (A2M) protein (ABIN491569) alpha-2-Macroglobulin (A2M) protein
Product cited in: Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, 2013 (PubMed).

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