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Plasminogen (PLG) Protein

Name

Plasminogen (PLG)
Synonyms DKFZp779M0222, Pg, AI649309, Ab1-346, PLG, LPA, wu:fb70e09, plg, DKFZp470G2422
Host
Origin (Gene)
Alternatives

Human
1 reference available
Catalog no. ABIN491590
Quantity 1.0 ml  (Sample concentration 1.0 mg/ml coup...)
Price 374.00 $   Plus shipping costs $45.00
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Additional Information
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Gene ID 5340
UniProt P00747
Format Resin
Description Immoblized human plasmin. We have immobilized human Lys plasmin on agarose resin by coupling of primary amines. Plasmin retains catalytic activity when coupled and may be used to efficiently activate single-chain tPA and uPA to the two-chain form (1). It may also be used to convert plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids.
Molecular Weight 85000

Application Details
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Concentration Sample concentration 1.0 mg/ml coupled, concentration varies by lot
Purity >95% by SDS-PAGE
Purification Chromatographically purified
Buffer 0.1M HEPES, 0.1M NaCl, 0.02% Sodium Azide, pH 7.4
Storage Store at 4°C

Publications
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Product Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.

Alternatives
Application Details Publications back to top

Alternatives for antigen "Plasminogen (PLG)", type "Proteins"
Hosts Human (9), Yeast (9), Escherichia Coli (E. coli) (8), Bovine (4), Mouse (3), Rat (2), Dog (1), Horse (1)
Reactivities Human (22), Mouse (Murine) (13), Cow (Bovine) (9), Rat (Rattus) (7), Chicken (4), Rabbit (4), Dog (Canine) (2), Horse (Equine) (2), Pig (Porcine) (1), Rhesus Monkey (1), Sheep (Ovine) (1)