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Details for Product No. ABIN491590

Plasminogen (PLG) Protein

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Protein Name
Synonyms Pg, AI649309, Ab1-346, LPA, wu:fb70e09, PLG, plg, DKFZp470G2422
Origin
»Alternatives Human
Host
Pubmed 1 reference available
Catalog no. ABIN491590
Quantity 1 mL
Price
374.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Purification Chromatographically purified
Purity >95% by SDS-PAGE
Alternative Name Plasmin
Background Immoblized human plasmin. We have immobilized human Lys plasmin on agarose resin by coupling of primary amines. Plasmin retains catalytic activity when coupled and may be used to efficiently activate single-chain tPA and uPA to the two-chain form (1). It may also be used to convert plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids.
Molecular Weight 85000
Gene ID 5340
UniProt P00747
Format Liquid
Concentration Sample concentration 1.0 mg/ml coupled, concentration varies by lot
Buffer 0.1M HEPES, 0.1M NaCl, 0.02% Sodium Azide, pH 7.4
Preservative Sodium azide
Storage 4 °C
Product cited in: Komissarov, Florova, Idell: "Effects of extracellular DNA on plasminogen activation and fibrinolysis." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 41949-62, 2011 (PubMed). Further details: Drs. Komissarov, Florova and Idell at the Univ. of Texas HSC used this reagent to investigate effects of DNA on the fibrinolysis pathway. DNA binding increases plasminogen activation by tPA/uPA as well as PAI-1 inhibition of tPA/uPA.

Alternatives for antigen "Plasminogen (PLG)", type "Proteins"
Hosts (12), (9), (9), (4), (3), (2), (1), (1)
Reactivities (27), (16), (11), (9), (6), (6), (2), (2), (1), (1), (1), (1)
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