BTN3A1 Protein (AA 30-254) (Fc Tag)

Catalog No. ABIN4949084

Product Details

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Protein Type: Recombinant

Protein Characteristics: AA 30-254

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BTN3A1 protein is labelled with Fc Tag.

Application: Functional Studies (Func)

Sequence: AA 30-254

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.8 kDa. As a result of glycosylation, the protein migrates as 55 kDa under reducing (R) condition, and 100-120 kDa under non-reducing (NR) condition (SDS-PAGE).

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Alternative Name: BTN3A1 (BTN3A1 Products)

Synonyms: BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein

Background: Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Molecular Weight: 50.8 kDa

Pathways: Activated T Cell Proliferation