IL23R Protein (AA 24-372) (Fc Tag)
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- Target See all IL23R Proteins
- IL23R (Interleukin 23 Receptor (IL23R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-372
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL23R protein is labelled with Fc Tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 24-372
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 66.8 kDa. As a result of glycosylation, the protein migrates as 90-100 kDa under reducing (R) condition, and 180-200 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL23R Protein
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Interleukin 23 Receptor (IL23R) (AA 24-355) protein (mFc Tag)
IL23R Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-355) protein (His tag)IL23R Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-374) protein (His tag)IL23R Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-354) protein (His tag)IL23R Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-353) protein (His tag)IL23R Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 23 Receptor (IL23R) (AA 24-355) (Active) protein (Fc Tag,AVI tag,Biotin)IL23R Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 23 Receptor (IL23R) protein (Fc Tag)IL23R Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 23 Receptor (IL23R) (AA 553-628) protein (GST tag)IL23R Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 23 Receptor (IL23R) (Active) protein (Fc Tag)IL23R Origin: Rat Host: HEK-293 Cells Recombinant (75.1+16.6) as determined by SDS-PAGE Active
Interleukin 23 Receptor (IL23R) (AA 377-629) protein (His tag)Crystallography grade IL23R Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- IL23R (Interleukin 23 Receptor (IL23R))
- Alternative Name
- IL-23R (IL23R Products)
- Synonyms
- IL-23R Protein, IL23R Protein, il-23r Protein, interleukin 23 receptor Protein, IL23R Protein, il23r Protein, Il23r Protein
- Background
- Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
- Molecular Weight
- 66.8 kDa
- NCBI Accession
- NP_653131
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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