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TMEM66 Protein (AA 195-339) (His-SUMO Tag)

TMEM66 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4975557
  • Target See all TMEM66 Proteins
    TMEM66 (Transmembrane Protein 66 (TMEM66))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 195-339
    Origin
    • 4
    • 3
    • 1
    Human
    Source
    • 6
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TMEM66 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    SDGQYSPPPY SEYPPFSHRY QRFTNSAGPP PPGFKSEFTG PQNTGHGATS GFGSAFTGQQ GYENSGPGFW TGLGTGGILG YLFGSNRAAT PFSDSWYYPS YPPSYPGTWN RAYSPLHGGS GSYSVCSNSD TKTRTASGYG GTRRR
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product TMEM66 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    TMEM66 (Transmembrane Protein 66 (TMEM66))
    Alternative Name
    SARAF (TMEM66 Products)
    Synonyms
    FOAP-7 Protein, SARAF Protein, XTP3 Protein, 1810045K07Rik Protein, tmem66 Protein, Tmem66 Protein, TMEM66 Protein, store-operated calcium entry associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor S homeolog Protein, transmembrane protein 66 Protein, SARAF Protein, Saraf Protein, saraf Protein, saraf.S Protein, MCYG_05410 Protein, MGYG_06464 Protein, Tsp_10089 Protein
    Background
    Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions.
    Molecular Weight
    31.48 kDa
    UniProt
    Q96BY9
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