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GPR75 Protein (AA 372-540) (His-SUMO Tag)

GPR75 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4975560
  • Target See all GPR75 Proteins
    GPR75 (G Protein-Coupled Receptor 75 (GPR75))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 372-540
    Origin
    • 9
    • 3
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GPR75 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    NPFIYSRNSA GLRRKVLWCL QYIGLGFFCC KQKTRLRAMG KGNLEVNRNK SSHHETNSAY MLSPKPQKKF VDQACGPSHS KESMVSPKIS AGHQHCGQSS STPINTRIEP YYSIYNSSPS QEESSPCNLQ PVNSFGFANS YIAMHYHTTN DLVQEYDSTS AKQIPVPSV
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product GPR75 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    GPR75 (G Protein-Coupled Receptor 75 (GPR75))
    Alternative Name
    GPR75 (GPR75 Products)
    Synonyms
    GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein
    Background
    G protein-coupled receptor that is activated by the chokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
    Molecular Weight
    34.9 kDa
    UniProt
    O95800
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