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PDCD6 Protein (AA 1-191, full length) (GST tag)

PDCD6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4975666
  • Target See all PDCD6 Proteins
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    Protein Type
    Recombinant
    Protein Characteristics
    full length, AA 1-191
    Origin
    • 7
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PDCD6 protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product PDCD6 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    Alternative Name
    PDCD6 (PDCD6 Products)
    Synonyms
    pdcd6 Protein, MGC52821 Protein, MGC132114 Protein, zgc:63952 Protein, PDCD6 Protein, ALG-2 Protein, PEF1B Protein, AV299538 Protein, Alg2 Protein, MA-3 Protein, PS2 Protein, alg-2 Protein, programmed cell death 6 L homeolog Protein, programmed cell death 6 Protein, pdcd6.L Protein, pdcd6 Protein, PDCD6 Protein, Pdcd6 Protein
    Background
    Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca2+-regulated signals along the death pathway . Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Ses to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca2+ affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.5 Publications
    Molecular Weight
    49.3 kDa
    UniProt
    O75340
    Pathways
    Positive Regulation of Endopeptidase Activity
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