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CBX7 Protein (AA 1-251, full length) (His tag)

CBX7 Origin: Human Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN4975696
  • Target See all CBX7 Proteins
    CBX7 (Chromobox Homolog 7 (CBX7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-251, full length
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Yeast
    Purification tag / Conjugate
    This CBX7 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA DADLAEGPPP WTPALPSSEV TVTDITANSI TVTFREAQAA EGFFRDRSGK F
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product CBX7 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CBX7 (Chromobox Homolog 7 (CBX7))
    Alternative Name
    CBX7 (CBX7 Products)
    Synonyms
    1600014J01Rik Protein, AI851678 Protein, D15Ertd417e Protein, zgc:110152 Protein, chromobox 7 Protein, chromobox homolog 7a Protein, CBX7 Protein, Cbx7 Protein, cbx7a Protein
    Background
    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
    Molecular Weight
    30.3 kDa
    UniProt
    O95931
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