RDH12 Protein (AA 1-316, full length) (His-SUMO Tag)
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- Target See all RDH12 Proteins
- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-316
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RDH12 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MLVTLGLLTS FFSFLYMVAP SIRKFFAGGV CRTNVQLPGK VVVITGANTG IGKETARELA SRGARVYIAC RDVLKGESAA SEIRVDTKNS QVLVRKLDLS DTKSIRAFAE GFLAEEKQLH ILINNAGVMM CPYSKTADGF ETHLGVNHLG HFLLTYLLLE QLKVSAPARV VNVSSVAHHI GKIPFHDLQS EKRYSRGFAY CHSKLANVLF TRELAKRLQG TGVTTYAVHP GVVRSELVRH SSLLCLLWRL FSPFVKTARE GAQTSLHCAL AEGLEPLSGK YFSDCKRTWV SPRARNNKTA ERLWNVSCEL LGIRWE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RDH12 Protein
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Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 39-316) protein (His tag)
RDH12 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) protein (GST tag)RDH12 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 217-316) protein (GST tag)RDH12 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) protein (Strep Tag)Crystallography grade RDH12 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) protein (Strep Tag)Crystallography grade RDH12 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316), (full length) protein (His-SUMO Tag)RDH12 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
- Alternative Name
- RDH12 (RDH12 Products)
- Synonyms
- wu:fj43a10 Protein, zgc:92430 Protein, A930033N07Rik Protein, LCA13 Protein, LCA3 Protein, RP53 Protein, SDR7C2 Protein, DSSDR2 Protein, retinol dehydrogenase 12 (all-trans/9-cis/11-cis) Protein, retinol dehydrogenase 12 Protein, Retinol dehydrogenase 12 Protein, RDH12 Protein, rdh12 Protein, MAV_1968 Protein, CC1G_02720 Protein, Bm1_36660 Protein, PTRG_03574 Protein, PTRG_05326 Protein, PTRG_08067 Protein, LOC100282710 Protein, LOC100285880 Protein, LOC100226769 Protein, Rdh12 Protein
- Background
- Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments.
- Molecular Weight
- 51.04 kDa
- UniProt
- Q96NR8
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