GALE Protein (AA 1-348, full length) (His-SUMO Tag)

Catalog No. ABIN4975737

Product Details

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Protein Type: Recombinant

Protein Characteristics: full length, AA 1-348

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GALE protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: MAEKVLVTGG AGYIGSHTVL ELLEAGYLPV VIDNFHNAFR GGGSLPESLR RVQELTGRSV EFEEMDILDQ GALQRLFKKY SFMAVIHFAG LKAVGESVQK PLDYYRVNLT GTIQLLEIMK AHGVKNLVFS SSATVYGNPQ YLPLDEAHPT GGCTNPYGKS KFFIEEMIRD LCQADKTWNA VLLRYFNPTG AHASGCIGED PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG HIAALRKLKE QCGCRIYNLG TGTGYSVLQM VQAMEKASGK KIPYKVVARR EGDVAACYAN PSLAQEELGW TAALGLDRMC EDLWRWQKQN PSGFGTQA

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Alternative Name: GALE (GALE Products)

Synonyms: GALE Protein, im:7147391 Protein, wu:fb05f01 Protein, zgc:136578 Protein, F15H21.11 Protein, F15H21_11 Protein, REB1 Protein, ROOT EPIDERMAL BULGER1 Protein, ROOT HAIR DEFECTIVE 1 Protein, UDP-GLUCOSE 4-EPIMERASE Protein, UGE4 Protein, ECK0748 Protein, galD Protein, JW0742 Protein, SMU.888 Protein, BA5505 Protein, BA5700 Protein, VFA0352 Protein, galE Protein, 2310002A12Rik Protein, AI323962 Protein, 1n569 Protein, xgale Protein, SDR1E1 Protein, UDP-galactose-4-epimerase Protein, NAD(P)-binding Rossmann-fold superfamily protein Protein, UDP-galactose 4-epimerase GalE Protein, UDP-glucose 4-epimerase Protein, UDP-glucose 4-epimerase GalE Protein, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase Protein, galactose-4-epimerase, UDP Protein, UDP-galactose-4-epimerase L homeolog Protein, GALE Protein, gale Protein, RHD1 Protein, ECs0787 Protein, galE Protein, galE1 Protein, galE2 Protein, STY0809 Protein, galE-2 Protein, SG0897 Protein, galD Protein, Ent638_1250 Protein, Gale Protein, gale.L Protein

Background: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.

Molecular Weight: 54.3 kDa

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process