HDAC8 Protein (AA 1-377, full length) (His-SUMO Tag)
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- Target See all HDAC8 Proteins
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-377
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HDAC8 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MEEPEEPADS GQSLVPVYIY SPEYVSMCDS PAKIPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HDAC8 Protein
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Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (GST tag)
HDAC8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) (AA 1-100) protein (GST tag)HDAC8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) protein (His tag)HDAC8 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (Strep Tag)Crystallography grade HDAC8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (Strep Tag)Crystallography grade HDAC8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 8 (HDAC8) (AA 1-377), (full length) protein (His-SUMO Tag)HDAC8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Alternative Name
- HDAC8 (HDAC8 Products)
- Synonyms
- HD8 Protein, CDLS5 Protein, HDACL1 Protein, MRXS6 Protein, RPD3 Protein, WTS Protein, 2610007D20Rik Protein, RGD1562895 Protein, wu:fd19a02 Protein, zgc:66196 Protein, ATHDA8 Protein, HDA8 Protein, HISTONE DEACETYLASE 8 Protein, T27G7.14 Protein, T27G7_14 Protein, histone deacetylase 8 Protein, histone deacetylase 8 Protein, histone deacetylase 8 L homeolog Protein, CC1G_05302 Protein, hdac8 Protein, HDAC8 Protein, Hdac8 Protein, hdac8.L Protein, HDA08 Protein
- Background
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
- Molecular Weight
- 57.7 kDa
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
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