WT1 Protein (AA 1-449, full length) (His-SUMO Tag)
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- Target See all WT1 Proteins
- WT1 (Wilms Tumor 1 (WT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-449, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WT1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS CQKKFARSDE LVRHHNMHQR NMTKLQLAL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product WT1 Protein
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Wilms Tumor 1 (WT1) (AA 1-449) protein (Strep Tag)
Crystallography grade WT1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Wilms Tumor 1 (WT1) (AA 157-445) protein (His tag)WT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Wilms Tumor 1 (WT1) (AA 349-439) protein (GST tag)WT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 (WT1) (AA 1-302) protein (GST tag)WT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 (WT1) (AA 147-446), (partial) protein (His tag)WT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Wilms Tumor 1 (WT1) (AA 1-449), (full length) protein (His-SUMO Tag)WT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- WT1 (Wilms Tumor 1 (WT1))
- Alternative Name
- WT1 (WT1 Products)
- Synonyms
- AWT1 Protein, EWS-WT1 Protein, GUD Protein, NPHS4 Protein, WAGR Protein, WIT-2 Protein, WT33 Protein, CWT1 Protein, WT1 Protein, XWT1a Protein, wt-1 Protein, wt1 Protein, xWT1 Protein, WT-1 Protein, gud Protein, wagr Protein, wt33 Protein, xwt1 Protein, wit-2 Protein, si:ch211-160j6.3 Protein, zgc:152697 Protein, D630046I19Rik Protein, Wt-1 Protein, XWT1b Protein, XeWT1 Protein, Wilms tumor 1 Protein, Wilms tumor 1 S homeolog Protein, wilms tumor 1b Protein, Wilms tumor protein Protein, Wilms tumor 1 homolog Protein, Wilms tumor 1 L homeolog Protein, WT1 Protein, wt1.S Protein, wt1 Protein, wt1b Protein, Wt1 Protein, wt1.L Protein
- Background
- Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
- Molecular Weight
- 65.2 kDa
- UniProt
- P19544
- Pathways
- Tube Formation
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