KMO Protein (AA 1-486, full length) (His tag)
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- Target See all KMO Proteins
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-486, full length
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This KMO protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MDSSVIQRKK VAVIGGGLVG SLQACFLAKR NFQIDVYEAR EDTRVATFTR GRSINLALSH RGRQALKAVG LEDQIVSQGI PMRARMIHSL SGKKSAIPYG TKSQYILSVS RENLNKDLLT AAEKYPNVKM HFNHRLLKCN PEEGMITVLG SDKVPKDVTC DLIVGCDGAY STVRSHLMKK PRFDYSQQYI PHGYMELTIP PKNGDYAMEP NYLHIWPRNT FMMIALPNMN KSFTCTLFMP FEEFEKLLTS NDVVDFFQKY FPDAIPLIGE KLLVQDFFLL PAQPMISVKC SSFHFKSHCV LLGDAAHAIV PFFGQGMNAG FEDCLVFDEL MDKFSNDLSL CLPVFSRLRI PDDHAISDLS MYNYIEMRAH VNSSWFIFQK NMERFLHAIM PSTFIPLYTM VTFSRIRYHE AVQRWHWQKK VINKGLFFLG SLIAISSTYL LIHYMSPRSF LRLRRPWNWI AHFRNTTCFP AKAVDSLEQI SNLISR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product KMO Protein
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Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) protein (Myc-DYKDDDDK Tag)
KMO Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 39-219) protein (His-IF2DI Tag)KMO Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-407) protein (GST tag)KMO Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486) protein (Strep Tag)Crystallography grade KMO Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-479) protein (Strep Tag)Crystallography grade KMO Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His-SUMO Tag)KMO Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His tag)KMO Origin: Human Host: Yeast Recombinant > 90 % SDS
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) protein (DYKDDDDK Tag)KMO Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- Alternative Name
- KMO (KMO Products)
- Synonyms
- AI046660 Protein, dJ317G22.1 Protein, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) Protein, kynurenine 3-monooxygenase Protein, Kmo Protein, KMO Protein
- Background
- Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
- Molecular Weight
- 57.8 kDa
- UniProt
- O15229
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