TCHP Protein (AA 1-498, full length) (His-SUMO Tag)
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- Target See all TCHP Proteins
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-498, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TCHP protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MALPTLPSYW CSQQRLNQQL ARQREQEARL RQQWEQNSRY FRMSDICSSK QAEWSSKTSY QRSMHAYQRE KMKEEKRRSL EARREKLRQL MQEEQDLLAR ELEELRLSMN LQERRIREQH GKLKSAKEEQ RKLIAEQLLY EHWKKNNPKL REMELDLHQK HVVNSWEMQK EEKKQQEATA EQENKRYENE YERARREALE RMKAEEERRQ LEDKLQAEAL LQQMEELKLK EVEATKLKKE QENLLKQRWE LERLEEERKQ MEAFRQKAEL GRFLRHQYNA QLSRRTQQIQ EELEADRRIL QALLEKEDES QRLHLARREQ VMADVAWMKQ AIEEQLQLER AREAELQMLL REEAKEMWEK REAEWARERS ARDRLMSEVL TGRQQQIQEK IEQNRRAQEE SLKHREQLIR NLEEVRELAR REKEESEKLK SARKQELEAQ VAERRLQAWE ADQQEEEEEE EARRVEQLSD ALLQQEAETM AEQGYRPKPY GHPKIAWN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TCHP Protein
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Trichoplein, Keratin Filament Binding (TCHP) (AA 1-497) protein (Strep Tag)
Crystallography grade TCHP Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Trichoplein, Keratin Filament Binding (TCHP) (AA 1-498) protein (Strep Tag)Crystallography grade TCHP Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Trichoplein, Keratin Filament Binding (TCHP) (AA 1-498), (full length) protein (His-SUMO Tag)TCHP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Alternative Name
- TCHP (TCHP Products)
- Synonyms
- TpMs Protein, A930031F18Rik Protein, AV279199 Protein, RGD1310813 Protein, zgc:136634 Protein, trichoplein keratin filament binding Protein, trichoplein, keratin filament binding Protein, trichoplein, keratin filament binding L homeolog Protein, TCHP Protein, tchp Protein, Tchp Protein, tchp.L Protein
- Background
- Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
- Molecular Weight
- 77.03 kDa
- UniProt
- Q9BT92
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