PSIP1 Protein (AA 1-530, full length) (His-SUMO Tag)
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- Target See all PSIP1 Proteins
- PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-530
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSIP1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTRDFKPGDL IFAKMKGYPH WPARVDEVPD GAVKPPTNKL PIFFFGTHET AFLGPKDIFP YSENKEKYGK PNKRKGFNEG LWEIDNNPKV KFSSQQAATK QSNASSDVEV EEKETSVSKE DTDHEEKASN EDVTKAVDIT TPKAARRGRK RKAEKQVETE EAGVVTTATA SVNLKVSPKR GRPAATEVKI PKPRGRPKMV KQPCPSESDI ITEEDKSKKK GQEEKQPKKQ PKKDEEGQKE EDKPRKEPDK KEGKKEVESK RKNLAKTGVT STSDSEEEGD DQEGEKKRKG GRNFQTAHRR NMLKGQHEKE AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK NSLKIDNLDV NRCIEALDEL ASLQVTMQQA QKHTEMITTL KKIRRFKVSQ VIMEKSTMLY NKFKNMFLVG EGDSVITQVL NKSLAEQRQH EEANKTKDQG KKGPNKKLEK EQTGSKTLNG GSDAQDGNQP QHNGESNEDS KDNHEASTKK KPSSEERETE ISLKDSTLDN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PSIP1 Protein
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PC4 and SFRS1 Interacting Protein 1 (PSIP1) (AA 1-50) protein (GST tag)
PSIP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
PC4 and SFRS1 Interacting Protein 1 (PSIP1) (AA 1-530) protein (Strep Tag)Crystallography grade PSIP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
PC4 and SFRS1 Interacting Protein 1 (PSIP1) (AA 1-528) protein (Strep Tag)Crystallography grade PSIP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
PC4 and SFRS1 Interacting Protein 1 (PSIP1) (AA 1-530), (full length) protein (His-SUMO Tag)PSIP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
PC4 and SFRS1 Interacting Protein 1 (PSIP1) proteinPSIP1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
PC4 and SFRS1 Interacting Protein 1 (PSIP1) proteinPSIP1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
- Alternative Name
- PSIP1 (PSIP1 Products)
- Synonyms
- PSIP1 Protein, im:7149861 Protein, zgc:109898 Protein, LEDGF Protein, p75 Protein, PSIP2 Protein, DFS70 Protein, PAIP Protein, p52 Protein, AA408851 Protein, AU015605 Protein, Dfs70 Protein, Ledgfa Protein, Ledgfb Protein, Psip2 Protein, Ledgf Protein, SBP75 Protein, LEDGF/p75 Protein, PC4 and SFRS1 interacting protein 1 S homeolog Protein, PC4 and SFRS1 interacting protein 1 Protein, PC4 and SFRS1 interacting protein 1a Protein, LEDGF/p75 transcription factor-like Protein, psip1.S Protein, PSIP1 Protein, psip1a Protein, psip1 Protein, Psip1 Protein
- Background
- Transcriptional coactivator involved in neuroepithelial st cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
- Molecular Weight
- 76.1 kDa
- UniProt
- O75475
- Pathways
- Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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