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GCKR Protein (AA 1-625, full length) (His-SUMO Tag)

GCKR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4975878
  • Target See all GCKR Proteins
    GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-625, full length
    Origin
    • 5
    • 2
    • 2
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GCKR protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MPGTKRFQHV IETPEPGKWE LSGYEAAVPI TEKSNPLTQD LDKADAENIV RLLGQCDAEI FQEEGQALST YQRLYSESIL TTMVQVAGKV QEVLKEPDGG LVVLSGGGTS GRMAFLMSVS FNQLMKGLGQ KPLYTYLIAG GDRSVVASRE GTEDSALHGI EELKKVAAGK KRVIVIGISV GLSAPFVAGQ MDCCMNNTAV FLPVLVGFNP VSMARNDPIE DWSSTFRQVA ERMQKMQEKQ KAFVLNPAIG PEGLSGSSRM KGGSATKILL ETLLLAAHKT VDQGIAASQR CLLEILRTFE RAHQVTYSQS PKIATLMKSV STSLEKKGHV YLVGWQTLGI IAIMDGVECI HTFGADFRDV RGFLIGDHSD MFNQKAELTN QGPQFTFSQE DFLTSILPSL TEIDTVVFIF TLDDNLTEVQ TIVEQVKEKT NHIQALAHST VGQTLPIPLK KLFPSIISIT WPLLFFEYEG NFIQKFQREL STKWVLNTVS TGAHVLLGKI LQNHMLDLRI SNSKLFWRAL AMLQRFSGQS KARCIESLLR AIHFPQPLSD DIRAAPISCH VQVAHEKEQV IPIALLSLLF RCSITEAQAH LAAAPSVCEA VRSALAGPGQ KRTADPLEIL EPDVQ
    Purification
    SDS-PAGE
    Purity
    > 90 %
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
    Alternative Name
    GCKR (GCKR Products)
    Synonyms
    FGQTL5 Protein, GKRP Protein, GLRE Protein, gckr Protein, glucokinase regulator Protein, glucokinase regulatory protein Protein, glucokinase regulator L homeolog Protein, GCKR Protein, Gckr Protein, gckr.L Protein
    Background
    Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
    Molecular Weight
    84.6 kDa
    UniProt
    Q14397
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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